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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKTIP
All Species:
38.18
Human Site:
T190
Identified Species:
64.62
UniProt:
Q9H8T0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8T0
NP_001012398.1
292
33128
T190
R
V
F
Y
K
I
D
T
A
S
P
L
N
P
E
Chimpanzee
Pan troglodytes
XP_001166382
293
33238
T190
R
V
F
Y
K
I
D
T
A
S
P
L
N
P
E
Rhesus Macaque
Macaca mulatta
XP_001085712
292
33132
T190
R
V
F
Y
K
I
D
T
A
S
P
L
N
P
E
Dog
Lupus familis
XP_863328
286
32246
T184
R
V
F
Y
K
I
D
T
A
S
P
L
N
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q64362
292
32923
T190
R
V
F
Y
K
I
D
T
T
S
P
L
N
P
E
Rat
Rattus norvegicus
Q5FVH4
292
32973
T190
R
V
F
Y
K
I
D
T
T
S
P
L
N
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520209
412
45602
T307
R
V
F
Y
K
I
D
T
T
G
P
L
N
P
E
Chicken
Gallus gallus
Q5ZJJ5
293
33286
T190
R
V
F
Y
K
I
D
T
T
S
P
L
N
P
E
Frog
Xenopus laevis
Q498F8
293
33438
T191
R
I
F
Y
K
I
D
T
T
S
P
L
N
P
E
Zebra Danio
Brachydanio rerio
Q7ZYX1
293
33182
T191
T
I
F
Y
K
I
N
T
M
E
P
L
N
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4V4
244
28114
E143
L
D
S
I
R
G
I
E
V
D
K
L
K
N
S
Honey Bee
Apis mellifera
XP_625209
266
31023
I165
L
I
Q
F
I
T
K
I
L
S
K
V
D
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784185
277
31591
F175
L
L
Y
A
R
R
V
F
Y
K
I
D
T
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P52490
153
17450
F52
S
P
Y
E
D
G
I
F
E
L
E
L
Y
L
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
95.2
N.A.
96.2
95.8
N.A.
59.9
87.3
82.9
78.1
N.A.
32.8
35.6
N.A.
53.4
Protein Similarity:
100
99.6
99.6
95.8
N.A.
97.9
98.6
N.A.
63.8
94.8
91.1
88
N.A.
46.9
59.2
N.A.
68.4
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
93.3
86.6
66.6
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
93.3
93.3
80
N.A.
13.3
40
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
34.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
29
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
65
0
0
8
0
8
8
0
0
% D
% Glu:
0
0
0
8
0
0
0
8
8
8
8
0
0
0
72
% E
% Phe:
0
0
72
8
0
0
0
15
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
15
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
22
0
8
8
72
15
8
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
72
0
8
0
0
8
15
0
8
8
8
% K
% Leu:
22
8
0
0
0
0
0
0
8
8
0
86
0
15
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
72
8
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
72
0
0
72
8
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
65
0
0
0
15
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
8
0
0
0
0
0
0
65
0
0
0
0
15
% S
% Thr:
8
0
0
0
0
8
0
72
36
0
0
0
8
0
0
% T
% Val:
0
58
0
0
0
0
8
0
8
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
72
0
0
0
0
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _